lithium

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I can’t think of a good Shakespeare quote, but there’s a little Milton below

Hello and good morning.  Welcome to another Thursday.  Please wipe your feet on your way in.

Just kidding.  It’s all crap here, anyway; don’t worry about wiping your feet.

I don’t have much to say today.  I don’t think I do, anyway.  Not that such a thing has tended to stop me in the past, but I don’t know.  I feel that maybe it’s at least slightly different this time.

Let’s see…updates.  I took my third small-dose of lithium this morning.  We’ll see how it goes.  I don’t think one would expect to see any major effects already, so be patient.  I tend to be patient, at least about some things.  What’s a doctor without patience, right?

Oh, yesterday afternoon, I had a near episode of esophageal spasm.  I’ve had that before‒the first big time it got me to the ER (I was already working in the hospital, so it wasn’t far to go), where I was checked for potential heart attack, which it was not, of course.

It wasn’t one yesterday, either, in case you’re worried.  It responded, albeit somewhat stubbornly, to drinking warmish water (and finally some Coke) to help soothe and relax my esophagus.  I don’t think anyone else in the office even noticed.

If it had been like the first time they would have noticed!  That time I had an apparent vaso-vagal response and my blood pressure went down way low, and I almost fainted.  That was part of why they brought me downstairs:  a BP of 80 over 40 in a 29 year old man who did have a history of heart surgery is somewhat concerning, and when you’re a medical resident at the hospital, they tend to treat you with urgency.

Okay, well, I think my esophagus yesterday had been irritated by my recent upper GI illness.  It’s not impossible, I guess, that lithium could have been involved.  I have noticed that, if I accidentally take too many multivitamins‒i.e., more than one in a day‒I am prone to esophageal spasm.  Perhaps electrolytes (etc.) are involved in at least increasing the chances of it happening.

I doubt they would be enough to trigger it all by themselves, though in severely misadjusted amounts they could cause severe pathologies of various kinds.  I wouldn’t be at all surprised if I found out electrolyte “imbalances” had caused such a thing all by themselves if they were off enough.  I don’t think that’s the case with me, though.  I have no other signs or symptoms of electrolyte dysfunction that I have noticed.

Okay, that’s enough discussion of that for the moment.  I don’t want to trigger an event by thinking about it too much, but since my upper GI tract is still a bit sensitive, it’s not impossible that I could accidentally do that.  “The mind is its own place, and of itself / can make a Hell of Heaven, a Heaven of Hell”, as someone said.

I think I may try to do another audio post today.  The few that I did recently seemed surprisingly popular, and conversely, my readership numbers have been going down pretty steadily since the last time I did one.  Maybe doing them in the first place was a bad idea, like giving a dog a taste of human food so that now it doesn’t want to eat its usual stuff.

Of course, dogs are practical, about food at least.  They rarely avoid their usual meals because they get treats.  They just eat them both.  At least, that’s how the dogs I have known have behaved.

Cats are a little more persnickety.  There are situations in which cats really will go dangerously hungry because the food on offer is not their favorite.  I would do that with eggplant.  It’s not the only food about which I could say that, but it’s the worst.

Anyway, again, I may do an audio today, partly as an experiment.  That may even become the subject of the audio, but I don’t think I’ll leave it at that (knowing me, which I do, at least a bit).  That would be kind of lame.  I guess we’ll see.

I might as well do something though.  I haven’t played or sang (or really listened to) any music in nearly two weeks, and I haven’t been reading, and I certainly haven’t been writing fiction.  I haven’t even been doing any exercises on Brilliant dot org.  And I’m possibly writing worse blog posts lately, and it’s causing people to stop reading.

I don’t know, maybe the declining readership numbers are related to the fact that I’ve been posting a bit earlier in the morning.  My insomnia has been generally increasing, and I’m getting up earlier and earlier, and so going to the office earlier and earlier.  Some people might just miss the posts because they’re arriving before they look at their notices (or email, or what have you) and other things follow and drown my little whimpers out.

So, if you’re interested, keep your eyes (and ears) open today for my possible audio thingy.  I’ll try not to disappoint, even though that’s something I just tend to do ceteris paribus.

Whatever the case, I hope you all have a truly good day.

TTFN

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Blog post after being out sick

I’m sorry about yesterday, everyone*.  I had some kind of stomach bug or had eaten something that was a bit off, something like that, and I stayed out of work, so I didn’t write a post.  Anyway, it was the sort of thing associated with nausea and vomiting, not really with much “lower GI” trouble, thankfully, but now it’s mostly worked its way out.  Certainly, I don’t feel like I’m going to throw up any more, at least not imminently.

It would be nice to be able to say confidently that I don’t think I will ever throw up again in my life‒if I could say so with good reasons‒but I don’t think it’s very likely that I’ll be able to say that honestly.

I need to stop “talking” about this, because it’s making me feel queasy again.

Anyway, I’m going to the office today, because I need to do payroll, and there will also be a bunch of crap on which I will need to catch up from yesterday.  That’s part of the reason I hate staying at the house from work even when I don’t feel well.  There’s always so much catch-up work after even one missed day.  And catch-up is too sweet and acidic for someone who has an icky tummy (ha ha).

I’m really not doing well, overall, in case you haven’t been able to tell, or in case you’re just new here, which is not impossible.  In my ongoing quest to try to correct some of this, I recently began encountering videos and some articles about low-dose lithium‒which, in non-low doses is used to treat bipolar disorder among other things**, as you may already know‒being beneficial for things like depression and even for preventing or curtailing certain forms of dementia (and, potentially, slowing aging, though that seems more speculative).

You can’t get the medical form of lithium without a prescription, which is probably good, since in those strong doses it can have significant toxicity, and people using it need to be monitored.  But there are other forms that one can get as supplements, and I ordered some recently (from a supposedly reputable brand).  They arrived yesterday evening, so I took one dose before bed‒thankfully they don’t appear to be irritating to my stomach‒and then one this morning.

It’s no big surprise that lithium is available in many forms.  It is the third most abundant element in the universe, having been created (in comparatively tiny amounts) when hydrogen and helium*** were made, in the aftermath of the Big Bang (technically we are in the aftermath of the Big Bang, and we could even say that we are in the ongoing process of the Big Bang).

But the lithium atom (the ion, really) is the active part in those various available compounds.  It is chemically quite similar to sodium and potassium (having that one electron in its outer shell, like they have) which are ubiquitous and essential electrolytes for numerous bodily processes.  Like them, in elemental form, lithium is a soft, light metal (indeed, the lightest metal), and like them it is highly reactive.

Anyway, enough of the chemistry trivia.  The point here is that I am trying to use it to treat my chronic dysthymia/depression if I can, which has been a difficult and long task at which I have been far from successful.

Probably part of that, or maybe even all of it, is related to my ASD, and so it may not be amenable to the same kinds of treatments that often work for others, and can be quite intractable by ordinary means, since the root problem is very different.  I don’t know how often I’ve had severe depressive episodes in the past in which it’s actually been autistic burnout or shutdown or related stuff.

There is growing data that things like cognitive behavioral therapy, which has relatively good results for neurotypical sufferers of depression, may actually be counterproductive in those with autism.  Autistic people tend already to analyze their thoughts, often too much, and to be disconnected from their feelings, though they have them and they can be overwhelming.  Analyzing it all just seems to increase that disconnect.

So, yeah, I’ve had very limited benefit from therapy, and similarly limited response to various kinds of antidepressants.  But maybe lithium will help.  I guess I will find out.

I would really like to try therapeutic psilocybin therapy, because based on the state of the science as I understand it so far, it works via entirely different mechanisms involving the “default mode network”, a series of brain areas/modules that are associated with self reference and the like.  But there is no legal use of psilocybin in Florida except in clinical studies.  (Thank you, Tricky Dick et al; may you and your ilk rot in Hell for as long a consecutive time as the length of misery to which you’ve contributed in so many others.)

The only places psilocybin therapy is legal in the US include Oregon (a very long way from me) and, ironically, DC.  So I don’t see how I would be able to avail myself of it in the current state of things.  And my brain is not my friend, so I am very leery of using psychedelics without supervision.

But I have to do something, or I’m pretty sure that pretty soon I am going to kill myself.  There is very little that holds me here day to day, and the very kind and good people who remain in my life are people I feel‒indeed, I am all but convinced‒would be at least as well off without me around, and probably better.

Have a good day, though.

*However many that may be.  It’s probably not a huge number.  Then again “everyone” can refer even to one person, so I guess it’s a tolerable pronoun, even if it might be slightly misleading in its usual connotations.

**It’s also pretty good for rechargeable batteries, and when added in the right proportions to deuterium/tritium can enhance the yield of thermonuclear weapons, because neutron capture leads to it decaying into tritium and…something else, another fusion product or some such; I need to review the specifics.  It’s never been my primary field of interest.

***Most helium currently on Earth is not helium from that early “elementogenesis” or whatever the official term is.  Rather, it is the product of radioactive decay of heavy elements, which often produces “alpha particles” which are just helium nuclei‒two protons and two neutrons‒and which can pretty readily grab electrons from the world about them and turn them into atoms.  This is why‒so I understand‒helium gas pockets are often found near concentrations of uranium ore and the like.